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Heart Imaging in Mice and Embryos

3D Imaging of Mice Cardiovascular Systems at Micron Resolution

High-Resolution Episcopic Microscopy (HREM) provides detailed 3D imaging of heart structures in mice, mice embryos, and chicken embryos, advancing cardiovascular research

Mouse Heart in 3D Imaged with High-Resolution Episcopic Microscopy (HREM)

Mouse Heart 3D Credit: Dr. Aseel Abbad (University of Nottingham, UK)

Overview

High-Resolution Episcopic Microscopy (HREM) provides precise 3D visualization of cardiac structures in mice, mice embryos, and chicken embryos with HREM with samples ranging under 1mm up to 25mm.

3D Heart Imaging in Small Models with HREM

High-Resolution Episcopic Microscopy (HREM) is a biomedical imaging technique that gives insights into the cardiac structures of small models such as mice and embryos. Whether you're studying the developing hearts of mice embryos or chicken embryos, HREM delivers the clarity and detail required to advance your cardiovascular research. By producing high-resolution, 3D images, this technology allows researchers to explore the complex anatomy of the heart in different species.

3D reconstructed image of a mouse embryo heart captured using High-Resolution Episcopic Microscopy (HREM)

How High-Resolution Episcopic Microscopy Enhances Heart Imaging

High-Throughput Imaging

HREM allows for detailed imaging in quantity allowing for knockout trials.

Detailed Visualization

The technique provides a clear view of the intricate structures of the heart, including valves, chambers, and vessels for further study.

Quantitative Analysis

HREM enables precise measurement in 3D which Enhances Heart Imaging and analysis of heart structures, which is critical for understanding heart development and disease.

Applications of HREM in Cardiac Research

HREM allows researchers study heart development and disease in animal models. Here are key applications:

  • Heart Development in Mice: HREM enables detailed 3D imaging of heart development in mice, offering critical insights into congenital heart.

  • Mice Embryo Cardiac Imaging: This technique allows for precise imaging of cardiac structures in mice embryos by imaging the full embryo, making it possible to study the heart at various stages of embryonic development.

  • Chicken Embryo Heart Analysis: HREM is also effective for imaging chicken embryos, providing valuable data for comparative studies in cardiac research.

  • Larger Samples: HREM can be used to image denser larger cardiac systems, such as pups

Frequently asked questions
Cross-sectional HREM image highlighting the intricate structure of a mouse heart

Gallery

Below is a gallery of HREM example images captured by ourselves and our customer base of Cardiovascular examples.​

Contact our High-Resolution Episcopic Microscopy (HREM) Experts

Want to know more about HREM, ask for a quote or get questions answered. Contact us and we can help answer all your questions.

Email:
hello@indigo-scientific.co.uk

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