Academic Publications
Publications and academic papers featuring High-Resolution Episcopic Microscopy (HREM).
23 Feb 2021
Multi-fluorescence high-resolution episcopic microscopy (MF-HREM) for three dimensional imaging of adult murine organs.
Claire Walsh, Natalie Holroyd, Eoin Finnerty, Sean G. Ryan, Paul W. Sweeney, Rebecca J. Shipley, Simon Walker-Samuel
28 Nov 2017
A predictive model of asymmetric morphogenesis from 3D reconstructions of mouse heart looping dynamics.
Le Garrec, J.F., J.N. Dominguez, A. Desgrange, K.D. Ivanovitch, E. Raphael, J.A. Bangham, M. Torres, E. Coen, T.J. Mohun, and S.M. Meilhac
7 Jul 2017
High-resolution Episcopic Microscopy (HREM) - Simple and Robust Protocols for Processing and Visualizing Organic Materials.
Geyer, S.H., B. Maurer-Gesek, L.F. Reissig and W.J. Weninger
27 Feb 2017
Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice.
Wilson, R., S.H. Geyer, L. Reissig, J. Rose, D. Szumska, E. Hardman, F. Prin, C. McGuire, R. Ramirez-Solis, J. White, A. Galli, C. Tudor, E. Tuck, C. Mazzeo, J.C. Smith, E. Robertson, D.J. Adams, T. Mohun, and W.J. Weninger
22 Sept 2016
High-throughput discovery of novel developmental phenotypes.
Dickinson, M.E., A.M. Flenniken, X. Ji, L. Teboul, M.D. Wong, J.K. White, T.F. Meehan, W.J. Weninger, H. Westerberg, H. Adissu, C.N. Baker, L. Bower, J.M. Brown, L.B. Caddle, F. Chiani, D. Clary, J. Cleak, M.J. Daly, J.M. Denegre, B. Doe, M.E. Dolan, S.M. Edie, H. Fuchs, V. Gailus-Durner, A. Galli, A. Gambadoro, J. Gallegos, S. Guo, N.R. Horner, C.W. Hsu, S.J. Johnson, S. Kalaga, L.C. Keith, L. Lanoue, T.N. Lawson, M. Lek, M. Mark, S. Marschall, J. Mason, M.L. McElwee, S. Newbigging, L.M. Nutter, K.A. Peterson, R. Ramirez-Solis, D.J. Rowland, E. Ryder, K.E. Samocha, J.R. Seavitt, M. Selloum, Z. Szoke-Kovacs, M. Tamura, A.G. Trainor, I. Tudose, S. Wakana, J. Warren, O. Wendling, D.B. West, L. Wong, A. Yoshiki, C. International Mouse Phenotyping, L. Jackson, I.C.d.l.S. Infrastructure Nationale Phenomin, L. Charles River, M.R.C. Harwell, P. Toronto Centre for, I. Wellcome Trust Sanger, R.B. Center, D.G. MacArthur, G.P. Tocchini-Valentini, X. Gao, P. Flicek, A. Bradley, W.C. Skarnes, M.J. Justice, H.E. Parkinson, M. Moore, S. Wells, R.E. Braun, K.L. Svenson, M.H. de Angelis, Y. Herault, T. Mohun, A.M. Mallon, R.M. Henkelman, S.D. Brown, D.J. Adams, K.C. Lloyd, C. McKerlie, A.L. Beaudet, M. Bucan, and S.A. Murray
22 Aug 2016
Morphogenesis of myocardial trabeculae in the mouse embryo.
Captur, G., R. Wilson, M.F. Bennett, G. Luxan, A. Nasis, J.L. de la Pompa, J.C. Moon, and T.J. Mohun
1 Jan 2016
Clarification of mammalian cloacal morphogenesis using high-resolution episcopic microscopy.
Huang, Y.C., F. Chen and X. Li
15 Apr 2015
Postmortem high-resolution episcopic microscopy (HREM) of small human fetal hearts.
Matsui, H., S.Y. Ho, T.J. Mohun and H.M. Gardiner
24 Dec 2014
The anatomy and development of the cardiac valves.
Spicer, D.E., J.M. Bridgeman, N.A. Brown, T.J. Mohun and R.H. Anderson
10 Oct 2014
Tbx1 coordinates addition of posterior second heart field progenitor cells to the arterial and venous poles of the heart.
Rana, M.S., M. Theveniau-Ruissy, C. De Bono, K. Mesbah, A. Francou, M. Rammah, J.N. Dominguez, M. Roux, B. Laforest, R.H. Anderson, T. Mohun, S. Zaffran, V.M. Christoffels, and R.G. Kelly
1 Jul 2014
What is aortic overriding?
Anderson, R.H., D.E. Spicer, G.W. Henry, C. Rigsby, A.M. Hlavacek, and T.J. Mohun
29 Dec 2013
A coming of age: advanced imaging technologies for characterising the developing mouse.
Norris, F.C., M.D. Wong, N.D. Greene, P.J. Scambler, T. Weaver, W.J. Weninger, T.J. Mohun, R.M. Henkelman, and M.F. Lythgoe
13 Jun 2013
A chick embryo with a yet unclassified type of cephalothoracopagus malformation and a hypothesis for explaining its genesis.
Maurer, B., S.H. Geyer and W.J. Weninger
26 Mar 2013
Clarification of the identity of the mammalian fifth pharyngeal arch artery.
Bamforth, S.D., B. Chaudhry, M. Bennett, R. Wilson, T.J. Mohun, L.H. Van Mierop, D.J. Henderson, and R.H. Anderson
2 Jul 2012
Normal and abnormal development of the intrapericardial arterial trunks in humans and mice.
Anderson, R.H., B. Chaudhry, T.J. Mohun, S.D. Bamforth, D. Hoyland, H.M. Phillips, S. Webb, A.F. Moorman, N.A. Brown, and D.J. Henderson
1 Jun 2012
Embedding embryos for episcopic fluorescence image capturing (EFIC).
Mohun, T.J. and W.J. Weninger
Three-dimensional and molecular analysis of the arterial pole of the developing human heart.
Sizarov, A., W.H. Lamers, T.J. Mohun, N.A. Brown, R.H. Anderson, and A.F. Moorman
1 Nov 2019
High‐resolution episcopic microscopy enables three‐dimensional visualization of plant morphology and development
Yuval Cinnamon, Olga Genin, Yiftah Yitzhak, Joseph Riov, Israel David, Felix Shaya, Anat Izhaki
23 Oct 2017
Morphology, topology and dimensions of the heart and arteries of genetically normal and mutant mouse embryos at stages S21-S23.
Geyer, S.H., L.F. Reissig, M. Husemann, C. Hofle, R. Wilson, F. Prin, D. Szumska, A. Galli, D.J. Adams, J. White, T.J. Mohun, and W.J. Weninger
15 Jun 2017
Key Questions Relating to Left Ventricular Noncompaction Cardiomyopathy: Is the Emperor Still Wearing Any Clothes?
Anderson, R.H., B. Jensen, T.J. Mohun, S.E. Petersen, N. Aung, F. Zemrak, R.N. Planken, and D.H. MacIver
24 Jan 2017
Temporally Distinct Six2-Positive Second Heart Field Progenitors Regulate Mammalian Heart
Zhou, Z., J. Wang, C. Guo, W. Chang, J. Zhuang, P. Zhu, and X. Li
7 Sept 2016
Insights regarding the normal and abnormal formation of the atrial and ventricular septal structures.
Anderson, R.H., N.A. Brown and T.J. Mohun
18 May 2016
Comparing homologous microscopic sections from multiple embryos using HREM.
Henkelman, R.M., M. Friedel, J.P. Lerch, R. Wilson and T. Mohun
25 Nov 2015
The anatomy and development of normal and abnormal coronary arteries.
Spicer, D.E., D.J. Henderson, B. Chaudhry, T.J. Mohun and R.H. Anderson
17 Feb 2015
iASPP, a previously unidentified regulator of desmosomes, prevents arrhythmogenic right ventricular cardiomyopathy (ARVC)-induced sudden death.
Notari, M., Y. Hu, G. Sutendra, Z. Dedeic, M. Lu, L. Dupays, A. Yavari, C.A. Carr, S. Zhong, A. Opel, A. Tinker, K. Clarke, H. Watkins, D.J. Ferguson, D.P. Kelsell, S. de Noronha, M.N. Sheppard, M. Hollinshead, T.J. Mohun, and X. Lu
1 Dec 2014
FGF10 promotes regional foetal cardiomyocyte proliferation and adult cardiomyocyte cell-cycle re-entry.
Rochais, F., R. Sturny, C.M. Chao, K. Mesbah, M. Bennett, T.J. Mohun, S. Bellusci, and R.G. Kelly
7 Oct 2014
Phenotyping structural abnormalities in mouse embryos using high-resolution episcopic microscopy.
Weninger, W.J., S.H. Geyer, A. Martineau, A. Galli, D.J. Adams, R. Wilson, and T.J. Mohun,
13 May 2014
Cor triatriatum or divided atriums: which approach provides the better understanding?
Bharucha, T., D.E. Spicer, T.J. Mohun, D. Black, G.W. Henry, and R.H. Anderson
23 Dec 2013
Tetralogy of Fallot: nosological, morphological, and morphogenetic considerations.
Anderson, R.H., D.E. Spicer, J.M. Giroud and T.J. Mohun
10 May 2013
Quantification of left ventricular trabeculae using fractal analysis.
Captur, G., V. Muthurangu, C. Cook, A.S. Flett, R. Wilson, A. Barison, D.M. Sado, S. Anderson, W.J. McKenna, T.J. Mohun, P.M. Elliott, and J.C. Moon
26 Feb 2013
Defects in the oval fossa: morphologic variations and impact on transcatheter closure.
Vettukattil, J.J., Z. Ahmed, A.P. Salmon, T. Mohun and R.H. Anderson
12 Jun 2012
Episcopic three-dimensional imaging of embryos.
Mohun, T.J. and W.J. Weninger
15 Feb 2012
Comparison of ex-vivo high-resolution episcopic microscopy with in-vivo four-dimensional high- resolution transvaginal sonography of the first-trimester fetal heart.
Gindes, L., H. Matsui, R. Achiron, T. Mohun, S.Y. Ho, and H. Gardiner,
1 Dec 2017
Cellular and morphological characterization of blastoderms from freshly laid broiler eggs.
Pokhrel, N., E. Ben-Tal Cohen, O. Genin, D. Sela-Donenfeld and Y. Cinnamon
27 Jul 2017
The independence of the infundibular building blocks in the setting of double-outlet right ventricle.
Aiello, V.D., D.E. Spicer, R.H. Anderson, N.A. Brown and T.J. Mohun
23 May 2017
A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5).
Geyer, S.H., L. Reissig, J. Rose, R. Wilson, F. Prin, D. Szumska, R. Ramirez-Solis, C. Tudor, J. White, T.J. Mohun, and W.J. Weninger
23 Dec 2016
ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome.
Zak, J., V. Vives, D. Szumska, A. Vernet, J.E. Schneider, P. Miller, E.A. Slee, S. Joss, Y. Lacassie, E. Chen, L.F. Escobar, M. Tucker, A.S. Aylsworth, H.A. Dubbs, A.T. Collins, J. Andrieux, A. Dieux-Coeslier, E. Haberlandt, D. Kotzot, D.A. Scott, M.J. Parker, Z. Zakaria, Y.S. Choy, D. Wieczorek, A.M. Innes, K.R. Jun, S. Zinner, F. Prin, C.A. Lygate, P. Pretorius, J.A. Rosenfeld, T.J. Mohun, and X. Lu
7 Sept 2016
Development and Morphology of the Ventricular Outflow Tracts.
Anderson, R.H., S. Mori, D.E. Spicer, N.A. Brown and T.J. Mohun
14 Jan 2016
Genetic dissection of Down syndrome- associated congenital heart defects using a new mouse mapping panel.
Lana-Elola, E., S. Watson-Scales, A. Slender, D. Gibbins, A. Martineau, C. Douglas, T. Mohun, E.M. Fisher, and V. Tybulewicz
25 Apr 2015
Clarifying the morphology of the ostium primum defect.
Anderson, R.H., T.J. Mohun and N.A. Brown
25 Jan 2015
The problems that exist when considering the anatomic variability between the channels that permit interventricular shunting.
ailliard, F., D.E. Spicer, T.J. Mohun, G.W. Henry and R.H. Anderson
20 Oct 2014
High-resolution episcopic microscopy (HREM): a tool for visualizing skin biopsies.
Geyer, S.H., M.M. Nohammer, M. Matha, L. Reissig, I.E. Tinhofer, and W.J. Weninger
29 Aug 2014
The development of septation in the four-chambered heart.
Anderson, R.H., D.E. Spicer, N.A. Brown and T.J. Mohun
5 Apr 2014
Abnormal cardiac formation in hypertrophic cardiomyopathy: fractal analysis of trabeculae and preclinical gene expression.
aptur, G., L.R. Lopes, V. Patel, C. Li, P. Bassett, P. Syrris, D.M. Sado, V. Maestrini, T.J. Mohun, W.J. McKenna, V. Muthurangu, P.M. Elliott, and J.C. Moon
11 Sept 2013
Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism.
Breckenridge, R.A., I. Piotrowska, K.E. Ng, T.J. Ragan, J.A. West, S. Kotecha, N. Towers, M. Bennett, P.C. Kienesberger, R.T. Smolenski, H.K. Siddall, J.L. Offer, M.M. Mocanu, D.M. Yelon, J.R. Dyck, J.L. Griffin, A.Y. Abramov, A.P. Gould, and T.J. Mohun
6 Apr 2013
Insights from cardiac development relevant to congenital defects and adult clinical anatomy.
Anderson, R.H., N.A. Brown, T.J. Mohun and A.F. Moorman
26 Oct 2012
Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing.
Lescroart, F., T. Mohun, S.M. Meilhac, M. Bennett and M. Buckingham
1 Jun 2012
Generation of volume data by episcopic three- dimensional imaging of embryos.
Mohun, T.J. and W.J. Weninger
21 Oct 2011
Imaging heart development using high-resolution episcopic microscopy.
Mohun, T.J. and W.J. Weninger