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High-Resolution Episcopic Microscopy (HREM) Examples

Example applications for the High-Resolution Episcopic Microscopy technique

HREM Examples Across Biological and Developmental Samples

Below are examples of data produced using our High-Resolution Episcopic Microscopy (HREM) systems, together with images of instruments used by our team and our users.

HREM provides high-contrast, 3D imaging of whole biological samples, making it ideal for embryos, organs, and soft tissues where detailed anatomical reconstruction is required. Image resolution and dataset size depend on system configuration and sample type, with individual sections reaching up to 20 megapixels.

Videos are displayed at reduced resolution for clarity and accessibility.

For application-specific examples or feasibility discussions, please contact us.

Mouse Embryos

Drosophila

Mouse Embryo Head

Embryonic Mice

Fruit & Plant Samples

Barley

HREM Ultra Scan

Embryonic Mice Heart

Zebrafish

Other Fish Samples

Single Shot HREM Image

Embryonic Mouse

Embryonic Hearts

Reproductive Systems

Single Shot HREM Image

Dual Channel Stack

3D STL Model

The 3D model shown here was generated from a High-Resolution Episcopic Microscopy (HREM) dataset of a mouse sample.

HREM captures thousands of perfectly aligned serial sections during block-face imaging. These 2D images are then computationally reconstructed into a volumetric dataset, allowing anatomical structures to be explored in three dimensions with micron-level detail.

This interactive model is a converted (and printable) representation of that reconstructed volume — not a CAD approximation.

Whole mouse embryo heart STL converted from 2D HREM images

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