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Applications / Serial Block Face Imaging

Serial Block Face Imaging for 3D Data

Image Dense Biological and Agricultural Samples in High Resolution

Capture 3D samples with serial block face imaging for resultant 2D stacks that align for 3-Dimensional reconstruction

Serial Block Face Imaging Instrument Sectioning a HREM Sample

Overview

Serial block face imaging produces 100s/1000s of images taken from a block surface. This methodology removes a section from the block to then image the surface of the block, each section being displaced from the image previously.

We offer systems to perform widefield serial block face imaging for a range of staining (such as HREM).

Benefits

High-Resolution Over Large Areas

Image whole samples using block face technologies in micro-macro sizes from <1mm- 60mm.

Dense and Complex Structures

Image a range of samples from whole embryos to individual organs, or citrus to barley.

3D reconstruction

Optical HREM systems, designed for block face imaging of larger samples.

Block Face Image Mouse imprinted on Block

Optical HREM Systems for Performing Serial Block Face Imaging

OHREM systems can be used for 3D data acquisition of whole samples by imaging the block face in resin, with a custom setup using the Micro or Ultra system will provide the best platform for resolution and sample size. 

Our systems offer an ideal solution for micron level resolution across samples up to 25-40mm in size.

Serial Block Face Images of Optical HREM Mouse Section

Why Choose HREM for 3D Imaging?

OHREM combines high-resolution 2D images with a volumetric model, giving up to 20-megapixel images that progressively, physically section the sample Ideal for imaging denser samples, that are harder to clear or are simply too big while providing low level resolution from 1-8 microns.

Contact our team

Contact our team to for a quote or more information on OHREM block face imaging.

Email:
hello@indigo-scientific.co.uk

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More Info

  • For more information or a quote use contact us

  • Browse the dedicated HREM page

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