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Microscopes / PRISM In Vivo Imaging Systems

In Vivo Imaging Systems

High-sensitivity in vivo imaging for preclinical research tracking bioluminescent and fluorescent signals in living small animal models over time, without the need to sacrifice the animal at each timepoint.

PRISM In Vivo Imaging System
In Vivo Imaging Systems

What is In Vivo Imaging

In vivo imaging allows researchers to visualise and quantify biological processes, such as tumour growth, infection spread, or gene expression, directly inside a living animal, repeatedly over time, rather than relying solely on endpoint dissection and histology. This reduces the number of animals required per study and captures how a process develops within the same subject, rather than inferring a timeline from separate animals at each stage.

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The PRISM range is built for high-sensitivity preclinical research, detecting low-level bioluminescent and fluorescent signals from labelled cells, pathogens or reporter constructs within a live animal, and quantifying signal change across the course of a study.

PRISM In Vivo Models

PRISM SWIR

PRISM SWIR

SWIR imaging platform enabling high-speed, multi-colour in vivo imaging across the NIR-II region.

PRISM Bio-Box

PRISM Bio-Box

Cost-effective bioluminescence imaging system for sensitive in vivo imaging of up to five mice.

In Vivo System

PRISM In Vivo EMCCD

EMCCD system for real-time bioluminescence and fluorescence imaging.

​PRISM SWIR In Vivo Imaging System

The PRISM™ SWIR system provides high-resolution in vivo imaging in the shortwave infrared (NIR-II) region, enabling clearer visualisation of fluorescent biomarkers deeper within tissue.

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  • SWIR (NIR-II) imaging for deeper tissue penetration and reduced auto fluorescence

  • Improved contrast and resolution compared with visible or standard NIR imaging

  • Multi-colour excitation with up to four user-defined wavelengths

  • Compatible with dyes such as Cy5, Cy7.5 and IRDye800CW

  • Auto-laser and auto-exposure modes for easier experiment setup

  • Excitation multiplexing with single-channel SWIR detection

  • Suitable for molecular and biomarker imaging in preclinical research

​PRISM EMCCD In Vivo Imaging System

The PRISM™ In Vivo Imaging System uses photon-counting EMCCD technology to deliver extremely sensitive real-time imaging for preclinical research.

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  • EMCCD camera capable of detecting single photons

  • Quantum efficiency above 90% between 550–750 nm

  • Real-time imaging with acquisition speeds up to 20 frames per second

  • Dual illumination from top-left and top-right for uniform fluorescence excitation

  • High-sensitivity bioluminescence and fluorescence imaging

  • 2D imaging with optional 3D signal localisation and depth estimation

  • Designed for detecting very weak optical signals in vivo

Contact our team

To discuss PRISM In Vivo Imaging Systems, compare system configurations or request detailed specifications, contact our team to explore the appropriate In Vivo platform for your application

Email:
hello@indigo-scientific.co.uk

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