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High Resolution Episcopic Microscopy (HREM) FAQ

  • Do you ship globally?
    Yes we ship and service OHREM's globally, service contracts are provided to help maintain your machine.
  • Can a demo unit be organised at my institution?
    Indigo is a small company and uses its size to give the best possible product for the best possible price to help researches get the most from their product. To keep costs low we do not have a facility to deliver demo stock to customers. Instead we invite customers to make specimens and send them to us to either be processed by us or one of our existing customer network. Get in contact to see how we can help.
  • What is the difference between HREM and OHREM
    HREM and OHREM are interchangeable however at Indigo we refer to OHREM as the system and HREM as the Technique. OHREM stands for Optical High Resolution Episcopic Microscopy.
  • Can the machine be adapted to different techniques?
    The system is flexible and we can help adapt the system to user requirements, get in contact to see what we can do.
  • Who Manufactures OHREM?
    The Optical HREM System is manufactured and sold by us here at Indigo Scientific.
  • How is the OHREM controlled?
    OHREM is controlled by a custom application designed by us here at Indigo to help deliver the most optimal performance and efficiency.
  • What is the maximum size of a specimen?
    A single shot optic (no scanning) is limited to the optical limit of 30mm for the standard system. However, with changes to the configuration the OHREM can achieve success of samples of 60mm wide. Get in touch to find out more.
  • What samples can be used?
    In theory it is down to the staining but already there has been great success in a variety of different specimens, we can offer interested parties imaging of there samples after following the protocol found in the members area. Get in touch to find out more.
  • How does the system (OHREM) work?
    HREM works by using a custom made microtone and optical setup made by Indigo Scientific to section a sample. The sample is imaged during sectioning giving an image series. Learn more about High Resolution Episcopic Microscopy Here. HREM sections 1-10 microns of a resin based block and images the surface.
  • How many samples/blocks can be imaged at once?
    Revision 1 OHREM systems can only image 1 block per section. OHREM 2 and an adapted OHREM 1 is capable of imaging 2 20 mm blocks or 4 10 mm blocks with the facility to expand this if required. It is worth noting a block can contain more than one sample, for example one block can contain 3 embryonic mouse hearts.
  • Are there different configurations/Addons?
    OHREM comes with many addons and configurations. Selections can include a scanning stage, dual/multi flourescence etc, contact us to get full details.
  • How does the system look?
    The Optical HREM system will vary based on the type of system you want but the main system will consist of a microtome unit and optics. The two major systems are the HREM Ultra and HREM Micro .
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