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Serial Block Face Imaging for 3D Data

Image Dense Biological and Agricultural Samples in High Resolution

Overview

Serial block face imaging produces 100s/1000s of images taken from a block surface. This methodology removes a section from the block to then image the surface of the block, each section being displaced from the image previously.

We offer systems to perform widefield serial block face imaging for a range of staining (such as HREM).

Benefits

High-resolution Over Large Areas

Image whole samples using block face technologies in micro-macro sizes from <1mm- 60mm using a combination of optics and imaging techniques combined with Optical HREM systems.

Dense and Complex Structures

Image a range of samples from whole embryos to individual organs, or citrus to barley using Optical HREM block face systems. With a combination of optical resolution and range of sample sizes produces a dynamic 3D imaging system.

3D reconstruction

Optical HREM systems, designed for block face imaging of larger samples, provide seamless acquisition of large volumetric datasets.

How Optical HREM Systems Perform Block Face Imaging

OHREM systems can be used for 3D data acquisition of whole samples by imaging the block face, with a custom setup using the Micro or Ultra system will provide the best platform for resolution and sample size.

HREM Block Face Imaging System Capturing Resin Mouse Sample

Why Choose HREM for 3D Imaging?

OHREM combines high-resolution 2D images with a volumetric model, giving up to 20-megapixel images that progressively, physically section the sample Ideal for imaging denser samples, that are harder to clear or are simply too big while providing low level resolution from 1-8 microns.

Serial Block Face Images of Optical HREM Mouse Section

Applications

Use OHREM block face imaging systems for a list of applications:

  • Whole Embryo Phenotyping and Development – Investigate subtle morphological images with complex structures in 2D and 3D with high resolution images.

  • Phenotyping of Crop Variety’s & Development – Examine phenotype traits that can be related to y drought tolerance, yield improvement etc.

  • Individual organs – Observe formation and differentiation of organs in developing organisms aiding in studies of congenital abnormalities.

Our instruments are used for HREM worldwide providing 3D data to many establishments for research for the above.

Contact our team

Contact our team to for a quote or more information on OHREM block face imaging.

Email:
hello@indigo-scientific.co.uk

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More Info

  • For more information or a quote use contact us

  • Browse the dedicated HREM page

Contact Us 

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Intech House

34-35 Wilbury Way

SG4 0TW

Hitchin

Hertfordshire 

United Kingdom

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